RT Book, Section A1 Maraqa, Nizar F. A2 Kline, Mark W. SR Print(0) ID 1182904467 T1 Cyclosporiasis T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182904467 RD 2024/10/04 AB Cyclospora cayetanensis is a coccidian parasite that causes acute or chronic, food- and waterborne diarrhea in both immunocompetent and immunocompromised hosts. Cyclospora is a distinct protozoan genus phylogenetically related to other coccidian parasites, including Cryptosporidium, Cystoisospora, Toxoplasma, and Sarcocystis. Initially described in 1979 as cyanobacteria-like (blue-green algae) bodies in the stools of patients in Papua New Guinea with prolonged diarrhea, anorexia, and fatigue, Cyclospora species are now known to be ubiquitous, infecting a variety of animals, birds, reptiles, insectivores, and rodents. However, C cayetanensis is the only species that is known to infect humans, and the role of animals as a natural reservoir is uncertain.