RT Book, Section
A1 Mirza, Ayesha
A2 Kline, Mark W.
SR Print(0)
ID 1182904529
T1 Free-Living Amebic Infections
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182904529
RD 2024/10/12
AB Organisms  of  the  genera  Naegleria,  Acanthamoeba,  and  Balamuthia,  also  known  as  “free-living”  amebae,  are  known  to  cause  meningoencephalitis  in  humans.  Another  free-living  ameba  genus,  Sappinia,  has  been  isolated  from  animals  but  is  rarely  isolated  from  humans.  Naegleria  fowleri  typically  causes  primary  amebic  meningoencephalitis  (PAM),  which  is  usually  fulminant  in  nature,  whereas  infections  caused  by  Acanthamoeba  and  Balamuthiamandrillaris  tend  to  be  more  indolent.  Like  Naegleria,  they  primarily  affect  the  central  nervous  system  (CNS)  causing  granulomatous  amebic  encephalitis  (GAE).  Several  species  of  Acanthamoeba  abound  and,  besides  GAE,  are  also  known  to  cause  amebic  keratitis.