RT Book, Section
A1 Jeha, George S.
A2 Kline, Mark W.
SR Print(0)
ID 1182918851
T1 Endocrine Abnormalities Causing Growth Impairment
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182918851
RD 2024/04/18
AB Several  pituitary  hormones  are  involved  in  growth  and  development.  Pituitary  hormones  contribute  to  growth  by  regulating  hormone  secretion  by  peripheral  glands,  which  act  on  tissues  to  increase  growth  and  modulate  the  secretion  of  the  pituitary  itself.  Growth  hormone  (GH)  from  the  pituitary,  thyroid  hormone,  and  sex  steroids  all  act  synergistically  at  the  growth  plates  of  long  bones  to  increase  height  during  childhood  and  adolescence.  Through  long  feedback  loops,  these  peripheral  hormones  regulate  the  hypothalamic  pituitary  signals  that  stimulate  their  own  release  but  also  modulate  other  hypothalamic  pituitary  signals  such  as  the  effect  of  thyroid  hormone  on  thyrotropin-releasing  hormone  (TRH)  and  thyroid-stimulating  hormone  (TSH)  secretion  as  well  as  its  effect  on  GH  secretion.