RT Book, Section A1 Rozenfeld, Ranna A. SR Print(0) ID 1152487703 T1 Acute Respiratory Distress Syndrome T2 The PICU Handbook YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259834370 LK accesspediatrics.mhmedical.com/content.aspx?aid=1152487703 RD 2024/03/28 AB Acute inflammation occurring as a result of either direct or indirect injuryHallmark of acute phase is diffuse alveolar damage via altered permeability of pulmonary endothelial and epithelial cellsLeads to accumulation of protein-rich fluid in alveoliInactivates surfactantLeads to hypoxia and impaired lung compliance