RT Book, Section A1 Rozenfeld, Ranna A. SR Print(0) ID 1152487887 T1 Shock T2 The PICU Handbook YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259834370 LK accesspediatrics.mhmedical.com/content.aspx?aid=1152487887 RD 2024/04/25 AB Shock is a state of circulatory dysfunction that results in insufficient oxygen delivery and other substrate to meet tissue metabolic demands.1 Inadequate oxygen delivery leads to a shift to anaerobic metabolism, eventually resulting in lactate production and metabolic acidosis.2 If this state persists, it can lead to multiple organ dysfunction and death.