RT Book, Section A1 Rozenfeld, Ranna A. SR Print(0) ID 1152489221 T1 Hyper/Hypothermia and the Febrile State T2 The PICU Handbook YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259834370 LK accesspediatrics.mhmedical.com/content.aspx?aid=1152489221 RD 2024/03/28 AB As endotherms, we autoregulate body temperature across a range of environmental conditions. Our temperature is intimately linked to our resting energy expenditure, which in turn drives our need for energy intake. Understanding the regulation of body temperature in the context of health and disease contributes to practice in the intensive care unit.The hypothalamus is the master thermostatBody temperature is maintained between 36°C and 37.5°CPatients above 38°C or 38.5°C are generally considered febrileFever is a regulated process in response to inflammatory cytokines and pyrogensTemperatures above 41°C are considered hyperthermicTemperatures below 36°C are considered hypothermic