RT Book, Section
A1 Rozenfeld, Ranna A.
SR Print(0)
ID 1152489233
T1 Anaphylaxis
T2 The PICU Handbook
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259834370
LK accesspediatrics.mhmedical.com/content.aspx?aid=1152489233
RD 2024/04/19
AB Etiology:  An  acute  multisystem  response  caused  by  a  severe  reaction  to  any  antigen,  such  as  a  drug,  vaccine,  food,  toxin,  plant,  or  venomClinical  Presentation:Systemic  vasodilation:HypotensionTachycardiaIncreased  capillary  permeability:Angioedema  –  may  lead  to  partial  or  complete  airway  obstructionWorsens  hypotensionPulmonary  vasoconstriction:Decreased  pulmonary  blood  flowIncreased  right  ventricular  afterloadDecreased  left  ventricular  preloadBronchoconstriction/bronchospasmRespiratory  distress  +/−  stridor,  wheezing,  or  bothHistamine  release:UrticariaNausea  and  vomiting