RT Book, Section A1 Saxena, Kirti A1 Kaur, Rajniderpal A1 Shah, Ajay A2 Kline, Mark W. SR Print(0) ID 1182924935 T1 Pediatric Depression and Bipolar Spectrum Disorders T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182924935 RD 2023/12/01 AB Affect regulation is a developmental acquisition that is impacted by environmental factors. For clinicians caring for children and adolescents, it is important to differentiate between normal mood fluctuations and emotions and pervasive mood disorders that significantly impact the child’s global functioning. A careful clinical assessment is necessary to make the diagnosis of mood disorders in children and adolescents, as there are no laboratory or neuroimaging tests that will ascertain the diagnosis. The clinical diagnosis of mood disorders is supported by research data obtained in epidemiological and longitudinal studies, as well as by clinical observations.