RT Book, Section A1 Mir, Adnan A2 Kline, Mark W. SR Print(0) ID 1182904948 T1 Functional Overview T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182904948 RD 2024/09/19 AB The skin, the largest organ in the body, includes 3 primary component layers: the epidermis, which is an epithelial layer; the dermis, which provides structural support and vascular supply and contains hair follicles, sweat glands, nerves, and other structures; and the subcutis, which is composed primarily of adipose tissue. Together, these structures play many roles including interface with the external environment, temperature regulation, endocrine function, sensory input, waste excretion, and sexual function. Diseases of the skin may affect any of these functions, and it is important to consider such potential complications when planning management.