RT Book, Section
A1 Abbott, Jordan K.
A1 Hauk, Pia J.
A2 Hay, Jr., William W.
A2 Levin, Myron J.
A2 Deterding, Robin R.
A2 Abzug, Mark J.
SR Print(0)
ID 1153313905
T1 Immunodeficiency
T2 Current Diagnosis & Treatment: Pediatrics, 24e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259862908
LK accesspediatrics.mhmedical.com/content.aspx?aid=1153313905
RD 2022/08/11
AB Immune  deficiencies  that  present  in  childhood  comprise  rare  disorders  that  have  been  characterized  by  a  combination  of  clinical  patterns,  immunologic  laboratory  tests,  and  often  molecular  identification  of  the  mutant  gene.  Children  with  primary  immunodeficiency  (PID)  commonly  present  with  recurrent  and/or  severe  bacterial  infections,  failure  to  thrive,  and/or  developmental  delay  as  a  result  of  infection.  Immunodeficiency  should  be  considered  when  infections  are  recurrent,  severe,  persistent,  resistant  to  standard  treatment,  or  caused  by  opportunistic  organisms.  Because  delayed  diagnosis  of  PIDs  is  common,  heightened  diagnostic  suspicion  is  warranted.