RT Book, Section
A1 Hershey, Gurjit K. Khurana
A2 Kline, Mark W.
SR Print(0)
ID 1182916877
T1 Childhood Asthma
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182916877
RD 2024/04/24
AB Asthma  is  a  chronic  condition  associated  with  significant  health  and  economic  burden  to  patients,  families,  and  society.  Its  symptoms  of  cough,  wheeze,  shortness  of  breath,  and  chest  tightness  are  associated  with  variable  airflow  limitation  that  is  at  least  partly  reversible.  Asthma  is  estimated  by  the  World  Health  Organization  to  affect  150  million  people  worldwide,  and  its  global  pharmacotherapeutic  costs  exceed  $5  billion  per  year.  Although  patients  suffering  from  asthma  share  similar  clinical  symptoms,  the  disease  itself  is  heterogeneous  in  terms  of  phenotypes  and  natural  history.  This  heterogeneity  is  compounded  by  combinations  of  environmental  exposures  that  occur  in  utero,  in  early  life,  and  across  the  life  span,  which  contribute  to  the  difficulty  in  both  studying  and  treating  asthma.  This  challenge  is  especially  evident  in  children,  for  whom  asthma  remains  the  leading  cause  of  emergency  care  and  hospitalization  rates  continue  to  rise.