RT Book, Section A1 Clark, Gary D. A2 Kline, Mark W. SR Print(0) ID 1182922410 T1 Microcephaly and Macrocephaly T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182922410 RD 2024/04/19 AB Human head size is largely determined by the size of the brain, cerebrospinal fluid (CSF) volume, and blood vessels and their content. Destructive processes or errors in proliferation of cells can lead to small heads that are less than the second percentile, a condition known as microcephaly. An increase in the volume of any 1 of these contents can lead to a head circumference greater than the 98th percentile, a condition known as macrocephaly. The development of a child can be affected depending on the processes that are involved in these disorders.