RT Book, Section A1 Risen, Sarah A1 Niedzwecki, Christian A2 Kline, Mark W. SR Print(0) ID 1182922461 T1 Trauma to the Nervous System T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182922461 RD 2024/03/29 AB Throughout training and in clinical practice, pediatricians will care for children who have sustained trauma to the central nervous system (CNS), which includes traumatic brain injury (TBI) and spinal cord injury (SCI). Unique to pediatrics, these injuries occur within the context of a developing nervous system. In addition to age-dependent acute physiologic responses to injury, CNS injury has the potential to disrupt synaptogenesis, axonal sprouting and pruning, myelination, and other ongoing molecular processes critical for optimal brain growth and function. Considering the essential role of the CNS in both automatic processes (eg, breathing, blood pressure control) and more sophisticated functions (eg, motor skills, language and learning, problem solving, behaviors and personality), brain or SCI can impair every aspect of a child’s daily life.