RT Book, Section A1 Benjamin, Lee S. A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. A2 Schafermeyer, Robert SR Print(0) ID 1155297399 T1 Thromboembolic Disease T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 5e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259860751 LK accesspediatrics.mhmedical.com/content.aspx?aid=1155297399 RD 2024/03/19 AB The greatest risk factor for thromboembolic disease in children is an indwelling central venous catheter.Disease patterns for pulmonary embolism in children and adolescents are similar to those in adults, yet diagnosis and management is often delayed or inappropriate.Arterial thromboembolism is more common in neonates and children with cardiac disorders, likely due to the use of umbilical artery catheters, cardiac catheters, extracorporeal membrane oxygenation (ECMO) circuits, and valvular disease.Anticoagulation is most commonly achieved acutely with unfractionated heparin or low-molecular-weight heparin (LMWH), followed by long-term anticoagulation with either LMWH or warfarin as experience with direct oral anticoagulants grows.