RT Book, Section
A1 Furtado, Nicholas
A2 Tenenbein, Milton
A2 Macias, Charles G.
A2 Sharieff, Ghazala Q.
A2 Yamamoto, Loren G.
A2 Schafermeyer, Robert
SR Print(0)
ID 1155427842
T1 Thyroid Disorders
T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 5e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259860751
LK accesspediatrics.mhmedical.com/content.aspx?aid=1155427842
RD 2023/06/10
AB The  most  common  disorder  causing  thyrotoxicosis  in  children  is  Graves’  disease.Thyroid  hormones  upregulate  β-adrenergic  receptors,  causing  symptoms  of  sympathetic  nervous  system  overactivity.Signs  of  sympathetic  hyperactivity  include  tremor,  brisk  deep  tendon  reflexes,  tachycardia,  arrhythmia,  flow  murmur,  and  congestive  heart  failure  (CHF).Precipitating  factors  for  thyroid  storm  in  a  patient  with  hyperthyroidism  are  stress,  palpation  of  a  goiter,  iodinated  contrast  dyes,  withdrawal  of  antithyroid  medications,  radioiodine  therapy,  and  thyroid  surgery.Thyroid  storm  is  suggested  by  severe  hyperpyrexia,  delirium  or  psychosis,  severe  gastrointestinal  hyperactivity,  hepatic  dysfunction  with  jaundice,  arrhythmia,  and  CHF.Treatment  consists  of  antithyroid  treatment  with  methimazole,  adrenergic  blockade,  and  supportive  management.