RT Book, Section A1 Wada, Randal K. A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. A2 Schafermeyer, Robert SR Print(0) ID 1155748217 T1 Blood Component Therapy T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 5e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259860751 LK accesspediatrics.mhmedical.com/content.aspx?aid=1155748217 RD 2024/03/29 AB It is common to underestimate quantitative blood loss in the setting of trauma. Careful and frequent monitoring of vital signs and hematocrit is critical in the detection of severe hemorrhage.Massive transfusion protocols exist to supply O-negative blood and other essential blood products for the resuscitation of the hemodynamically unstable trauma patient.Mild-to-severe reactions can occur during the transfusion process including fever, chills, nausea, hypotension, or shock. Whether this is caused by blood type incompatibility, antibodies to donor cells, or blood product contamination, the transfusion must be stopped immediately and the symptoms of the reaction treated aggressively.