RT Book, Section A1 Laufer, Miriam K. A2 Shah, Samir S. A2 Kemper, Alex R. A2 Ratner, Adam J. SR Print(0) ID 1157324376 T1 Malaria T2 Pediatric Infectious Diseases: Essentials for Practice, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861536 LK accesspediatrics.mhmedical.com/content.aspx?aid=1157324376 RD 2024/04/19 AB Malaria is a leading cause of childhood morbidity and mortality worldwide, with approximately 212 million cases occurring in 2015. The burden of this disease is borne largely by children in sub-Saharan Africa, where approximately 90% of infections and 70% of malaria-associated deaths occur.1,2 In the United States, local malaria transmission, which was once endemic, has been extremely rare since the 1950s.3 However, American physicians continue to encounter patients with malaria, mostly immigrants, refugees, returned travelers, and military personnel, who acquired their infections in endemic areas. An average of 1700 malaria cases and 13 related deaths occur in the United States every year. Most of the cases were acquired in sub-Saharan Africa and caused by Plasmodium falciparum, although Plasmodium species infections are imported from other malaria-endemic regions, as well.4