RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164061384 T1 Alpers Syndrome T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164061384 RD 2024/04/19 AB A progressive mitochondrial disorder that predominantly affects the gray matter of the brain and is characterized by the clinical triad of progressive developmental delay, intractable seizures, and liver failure. The prognosis is generally poor and exacerbations can be triggered by stress or infections.