RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164064288 T1 Canavan Disease (CD) T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164064288 RD 2024/10/15 AB A progressive leukodystrophy caused by spongy degeneration of the central nervous system. The clinical triad of hypotonia, macrocephaly, and lack of head control in an infant more than 3 to 5 months old should raise suspicion for this disorder.