RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164067165 T1 Cri-du-Chat Syndrome T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164067165 RD 2024/10/07 AB This is a medical condition characterized by infants that have a cry that is similar to a meowing kitten as a result of laryngeal dysfunction. The clinical features include a high-pitched, cat-like cry in the newborn period, severe mental retardation, facial anomalies, scoliosis, muscular hypotonia, and congenital cardiac (eg, atrial and/or ventricular septal defects, tetralogy of Fallot, pulmonary stenosis, tricuspid regurgitation, patent ductus arteriosus, pulmonary hypertension) and renal defects (eg, horseshoe kidneys, renal ectopia, hydronephrosis). About one-third of children lose the cry by age of 2 years. Affected individuals may also present with cleft lip and palate, preauricular tags, thymic dysplasia, intestinal malrotation, and hypospadias.