RT Book, Section
A1 Bissonnette, Bruno
A1 Luginbuehl, Igor
A1 Engelhardt, Thomas
SR Print(0)
ID 1164068230
T1 Donohue Syndrome
T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259861789
LK accesspediatrics.mhmedical.com/content.aspx?aid=1164068230
RD 2022/08/15
AB It  is  an  extremely  rare  inherited  condition  caused  by  resistance  to  insulin  with  growth  deficiency  and  characterized  by  dysmorphic  facies  (“elfin-like”),  severe  growth  retardation,  hirsutism,  and  multiple  endocrine  disorders.  Other  features  include  low  birth  weight,  skin  abnormalities  (acanthosis  nigricans  and  pachyderma),  and  significant  enlargement  of  the  breast  and  clitoris  in  females  and  the  penis  in  males.  Hypertrophic  cardiomyopathy  has  also  been  observed  in  these  patients.