RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164068742 T1 Ehlers-Danlos Syndrome (EDS): An Overview T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164068742 RD 2024/11/01 AB The Ehlers-Danlos Syndromes (EDS) form a large group of related disorders that are caused by genetic defects in collagen, either by lack of amount or being structurally dysfunctional. The clinical features are associated with alterations of the skin, muscles, skeleton, and blood vessels. Hyperelasticity of the skin, hypermobility of the joints leading easily to dislocations, vascular wall anomalies causing aneurysms and hemorrhages, are pathognomic signs of the disease.