RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164069162 T1 Erythema Multiforme (EM) T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164069162 RD 2024/04/23 AB An acute mucocutaneous hypersensitivity reaction of variable severity characterized by symmetrical skin eruptions, with or without mucous membrane lesions. This remains a skin condition for which the cause is unknown. It is a type of erythema possibly mediated by deposition of IgM-bound complexes in the superficial microvasculature of the skin and oral mucous membrane (occasionally the eyes) that usually follows an infection or drug exposure. The clinical presentation tends to be fulminant in children. However, the peak incidence is in the second and third decades of life.