RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164070298 T1 Freeman-Sheldon Syndrome (FSS) T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164070298 RD 2024/03/28 AB Freeman-Sheldon Syndrome, or distal arthrogryposis Type 2A, is a rare genetic malformative disorder characterized by microstomia, congenital myopathy and dysplasia characterized by multiple contractures, abnormalities of the head and face, defective development of the hands and feet, and skeletal malformations. The facial muscle contracture produces the typical “whistling face” appearance. Anesthetic issues include difficult intravenous access, difficult airway, and postoperative pulmonary complications. Although an association with malignant hyperthermia has been suggested, this has not been confirmed.