RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164070857 T1 Glanzmann’s Thrombasthenia T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164070857 RD 2024/10/04 AB Genetic platelet disorder resulting in blood clotting disorder and hemorrhage. The disease is usually diagnosed in young ages after epistaxis or mucocutaneous bleeding. Complaints such as easy bruising, muscle hematomas, hemarthrosis gastrointestinal bleeding, menorrhagia, and hematuria appear in further stages of life. This medical condition is associated with life-threatening conditions when the patient is exposed to stress (eg, surgery, anesthesia). It is an extremely rare coagulopathy disorder in which the platelets contain defective or low levels of glycoprotein IIb/IIIa (GpIIb/IIIa), which is a receptor for fibrinogen. As a result, no fibrinogen bridging of platelets to other platelets can occur, and the bleeding time is significantly prolonged.