RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164072708 T1 Hereditary Sensory and Autonomic Neuropathy Type III (HSAN III) T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164072708 RD 2024/03/28 AB Familial dysautonomia is a genetic disorder that affects involuntary actions such as digestion, breathing, production of tears, and the regulation of blood pressure and body temperature. Problems related to this disorder first appear during infancy. Early symptoms include hypotonia, feeding difficulties, poor growth, lack of tears, frequent lung infections, and difficulty maintaining body temperature. Other features include alterations of the taste and the perception of pain, heat, and cold. Older infants and young children with familial dysautonomia show cyanosis when these infants hold their breath which may cause a bluish appearance of the skin or lips or fainting. This breath-holding behavior usually stops by age 6. Developmental milestones, such as walking and speech, are usually delayed, although some affected individuals show no signs of developmental delay.