RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164073000 T1 Hirschsprung Syndrome T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164073000 RD 2024/10/10 AB Congenital disorder characterized by absence of enteric ganglia causing a megacolon. Other features include variable length of denervated intestinal loops leading to chronic constipation, abdominal distension, and fecal impaction in infancy, with growth retardation. The absence of meconium within 48 hours following delivery is suggestive of the disease. Normally, 90% of babies pass their first meconium within 24 hours, and 99% within 48 hours.