RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164073053 T1 Histiocytosis T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164073053 RD 2024/03/28 AB Group of disorders that have in common, as a primary event, the accumulation and infiltration of histiocytes, monocytes, macrophages, and dendritic cells in the affected tissues. It involves mainly the skin, bones, brain, lungs, spleen, and liver. It is often characterized by the presence of nonmalignant growths as a result of accumulation of histiocytes. This is associated with a very poor prognosis (70% mortality).