RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164073080 T1 Holt-Oram Syndrome (HOS) T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164073080 RD 2024/03/29 AB Genetically transmitted malformation syndrome characterized by congenital anomalies of the upper extremity malformations involving radial, thenar (hypoplasia or triphalangeal thumb), or carpal bones associated with heart disease (ventricular and atrial septal defect as well as conduction problems). This medical condition can also affect other part of the skeletal structure. It is reported that approximately 75% of individuals with Holt-Oram Syndrome have severe heart problems.