RT Book, Section
A1 Bissonnette, Bruno
A1 Luginbuehl, Igor
A1 Engelhardt, Thomas
SR Print(0)
ID 1164073495
T1 Hypophosphatasia
T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259861789
LK accesspediatrics.mhmedical.com/content.aspx?aid=1164073495
RD 2024/04/20
AB Hypophosphatasia  (HPP)  is  a  rare  genetic  disorder  characterized  by  the  abnormal  development  of  bones  (similar  to  vitamin  D-resistant  rickets)  and  teeth.  Other  features  in  this  inherited  inborn  error  of  metabolism  include  failure  to  thrive,  movement  disorders,  and  low  plasma  levels  of  alkaline  phosphatase.  HPP  is  an  extremely  variable  disorder.  Six  major  clinical  forms  have  been  identified  based  primarily  upon  the  age  of  onset  of  symptoms  and  diagnosis.