RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164074033 T1 Isotretinoin Embryopathy-Like Syndrome T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164074033 RD 2024/10/03 AB Teratogenetic polymalformative syndrome includ­ing malformations of the head, ears, and face. The most significant condition include the heart (conotruncal defects and aortic arch anomalies), and central nervous system (hydrocephalus and posterior fossae anomalies). This is caused by isotretinoin (vitamin A analogue) during pregnancy for the treatment of acne.