RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164076382 T1 Launois Syndrome T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164076382 RD 2024/04/23 AB Gigantism caused by excessive growth hormone (GH) secretion usually because of a pituitary adenoma that normally occurs before the epiphyses are fused in comparison with acromegaly that occurs after fusion of the epiphyses. The onset of the disease is usually prior to puberty and is often associated to muscle weakness, headache, visual defects, and articulation pain. Males are more commonly affected.