RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164076458 T1 Leber Hereditary Optic Neuropathy (LHON) T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164076458 RD 2024/03/28 AB It is a rare hereditary form of optic atrophy that usually affects young males. Characterized by sudden bilateral cloudiness of vision, followed by scotoma, rapid deterioration of central vision, and occasional color vision disorders. Associated with atrophy of the optic nerve fibers and retinae. Considered a mitochondrial disease. Cardiac conduction defects have been reported with this condition. Blindness is usually seen before the age of 40 years.