RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164077951 T1 Mastocytosis T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164077951 RD 2024/10/10 AB It is a medical condition that leads to accumulation and degranulation of mast cells (mastocytosis) in the skin, bone marrow, liver, spleen, gastrointestinal tract, and lymph nodes. Systemic mastocytosis occurs in approximately 10% of all cases. There are seven subtypes of this disorder based on the clinical presentation, the onset of the symptoms, and the prognosis (see below). The frequency of perioperative anaphylaxis appears to be higher in mastocytosis patients than in the general population.