RT Book, Section
A1 Bissonnette, Bruno
A1 Luginbuehl, Igor
A1 Engelhardt, Thomas
SR Print(0)
ID 1164078034
T1 McCune-Albright Syndrome
T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259861789
LK accesspediatrics.mhmedical.com/content.aspx?aid=1164078034
RD 2024/04/16
AB It  is  characterized  by  the  triad  of  polyostotic  fibrous  dysplasia,  café-au-lait  skin  pigmentation,  and  autonomous  endocrine  hyperfunction.  The  most  common  form  of  autonomous  endocrine  hyperfunction  is  gonadotropin-independent  precocious  puberty,  but  affected  individuals  also  may  have  hyperparathyroidism,  hyperthyroidism  Cushing’s  disease,  hypercorticism,  hyperprolactinemia,  pituitary  gigantism,  or  acromegaly.  Nonendocrine  abnormalities  in  this  disorder  include  chronic  liver  disease,  tachycardia,  and  rarely  sudden  death  as  a  result  of  cardiac  arrhythmias.