RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164079718 T1 Myasthenia Gravis T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164079718 RD 2024/03/29 AB It is a neuromuscular disorder characterized by significant muscle weakness and rapid muscle fatigue during mild exercise, such as a slow walk. Congenital myasthenias are present in the first years of childhood. Spontaneous forms of Myastheria Gravis (MS) are usually recognized during adulthood. Usually apparent during adulthood, the onset of the symptoms occurs at any age and spontaneously. Most individuals present eyelid ptosis, diplopia, and excessive muscle fatigue following exercise. Other clinical features commonly include dysarthria, dysphagia, and proximal limb weakness. Approximately 10% may develop potentially life-threatening complications as a consequence of severe respiratory depression (myasthenic crisis).