RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164079741 T1 Myhre Syndrome T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164079741 RD 2024/03/29 AB It is a syndrome characterized by laryngotracheal stenosis, mental retardation, short stature, maxillary hypoplasia, prognathism, severe midface hypoplasia, short palpebral fissures, short philtrum, microstomia, generalized muscle hypertrophy, decreased joint mobility, cryptorchidism, cardiac anomaly, and sensorineural deafness. The cardiovascular anomaly include congenital heart defects, long- and short-stenotic stenosis of the aorta and peripheral arteries, pericardial effusion, constrictive pericarditis, restrictive cardiomyopathy, and hypertension. The involvement of the respiratory system shows choanal stenosis, laryngotracheal narrowing, obstructive airway disease, and restrictive pulmonary disease. A pyloric stenosis is often seen and surely a reason for early surgery. The onset of the disease is at infancy or early childhood.