RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164080823 T1 Osteopetrosis T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164080823 RD 2024/03/29 AB Heterogenous genetic disorder of bone metabolism characterized by deficient osteoclast function with defective bone resorption and increased bone mass. Depending on the mode of inheritance, its course can be either uniformly fatal with pancytopenia, recurrent pathologic fractures, blindness, and other neurologic symptoms, or it can exist in a much milder form with later manifestation and favorable prognosis.