RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164086415 T1 Thrombotic Thrombocytopenic Purpura (TTP) T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accesspediatrics.mhmedical.com/content.aspx?aid=1164086415 RD 2024/04/16 AB Systemic disease characterized by platelet aggregation into widespread platelet thrombi and resulting occlusion of the microvasculature. This disease is closely related to and overlaps with Hemolytic Uremic Syndrome (HUS) within the broader definition of thrombotic microangiopathies. Clinical features include seizure, hemiplegia, fatigue, abdominal pain, arthralgias, neurological deficit, and renal insufficiency. Idiopathic presentation with a 60% female preponderance.