RT Book, Section A1 Gomella, Tricia Lacy A1 Eyal, Fabien G. A1 Bany-Mohammed, Fayez SR Print(0) ID 1168356873 T1 Hypoglycemia T2 Gomella's Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 8e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781259644818 LK accesspediatrics.mhmedical.com/content.aspx?aid=1168356873 RD 2024/03/29 AB An infant has a low blood glucose level on bedside glucose testing.Hypoglycemia is the most common metabolic problem in neonates in the newborn nursery and neonatal intensive care unit (NICU). Neonatal hypoglycemia occurs most often (47%–52%) in at-risk infants who are small for gestational age (SGA) or large for gestational age (LGA), late preterm infants, or infants of diabetic mothers (IDM). It can occur in up to 10% of healthy term newborns. There is controversy surrounding neonatal hypoglycemia, including no absolute definition of hypoglycemia. Low glucose values may or may not result in clinical signs; the low value and duration of hypoglycemia that result in neurologic injury are unknown, and there are differing viewpoints from the American Academy of Pediatrics (AAP) and Pediatric Endocrine Society (PES) on hypoglycemia screening and guidelines. There is agreement that there are 2 forms of hypoglycemia in neonates: transitional hypoglycemia, which usually resolves within 48 hours after birth, and persistent hypoglycemia, which continues and can be pathologic. The AAP Committee on Fetus and Newborn states that the “absolute definition of hypoglycemia as a specific value or range cannot be given, as no evidence-based studies can define what clinically relevant neonatal hypoglycemia is.” Hypoglycemia definitions are based on treatment recommendation target threshold values: