RT Book, Section A1 Gomella, Tricia Lacy A1 Eyal, Fabien G. A1 Bany-Mohammed, Fayez SR Print(0) ID 1168358073 T1 Neural Tube Defects T2 Gomella's Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 8e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781259644818 LK accesspediatrics.mhmedical.com/content.aspx?aid=1168358073 RD 2024/11/10 AB Neural tube defects (NTDs) are malformations of the developing brain and spinal cord. In normal development, the closure of the neural tube occurs over a 4- to 6-day period with completion around the 29th day postconception, often before a woman has realized that she is pregnant. Most current hypotheses consider NTDs to be defects from failure of a neural tube closure rather than the reopening of a previously closed tube. The nomenclature for NTDs is not standardized; frequently used terms are as follows: