RT Book, Section A1 Stiles, Charles Tad A2 Stone, C. Keith A2 Humphries, Roger L. A2 Drigalla, Dorian A2 Stephan, Maria SR Print(0) ID 1176572234 T1 Fever T2 CURRENT Diagnosis & Treatment: Pediatric Emergency Medicine YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 9780071799454 LK accesspediatrics.mhmedical.com/content.aspx?aid=1176572234 RD 2024/03/28 AB Fever constitutes approximately 20% of visits to emergency departments nationwide. It is also the most common pediatric emergency concern. Fever is defined as body temperature greater than 38°C (100.4°F). Fever is induced by exogenous pyrogens from invading organisms and by endogenous pyrogens that are released by immune mediating cells to fight infectious pathogens. The pyrogens cause the body’s central “thermostat” in the hypothalamus to reset.