RT Book, Section A1 Hanna, Melisha G. A1 Bock, Margret E. A2 Bunik, Maya A2 Hay, William W. A2 Levin, Myron J. A2 Abzug, Mark J. SR Print(0) ID 1190365382 T1 Fluid, Electrolyte, & Acid–Base Disorders & Therapy T2 Current Diagnosis & Treatment: Pediatrics, 26e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264269983 LK accesspediatrics.mhmedical.com/content.aspx?aid=1190365382 RD 2023/03/28 AB Total body water (TBW) constitutes 50%–75% of the total body mass, depending on age, sex, and fat content. After an initial brisk postnatal diuresis, the TBW slowly decreases to the adult range near puberty. TBW is divided into the intracellular and extracellular spaces. Intracellular fluid (ICF) accounts for two-thirds of the TBW and extracellular fluid (ECF) for one-third. The ECF is further compartmentalized into plasma (intravascular) volume and interstitial fluid (ISF).