RT Book, Section A1 Feucht, Cynthia A2 Patel, Dilip R. A2 Greydanus, Donald E. A2 Baker, Robert J. SR Print(0) ID 6983483 T1 Appendix D. Analgesic and Nonsteroidal Anti-Inflammatory Drugs T2 Pediatric Practice: Sports Medicine YR 2009 FD 2009 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-149677-3 LK accesspediatrics.mhmedical.com/content.aspx?aid=6983483 RD 2024/03/29 AB Table Graphic Jump LocationTable D-1. Anti-Inflammatory DrugsView Table||Download (.pdf)Table D-1. Anti-Inflammatory DrugsGeneric NameBrand NameAdult DosagePediatric DosageNon-Steroidal Anti-Inflammatory DrugsDiclofenac sodiumVoltaren®100–200 mg daily2–3 mg/kg/d(2–4 divided doses)(2–4 divided doses)*ER given 1–2 × daily*Diclofenac potassiumCataflam®100–200 mg daily2–3 mg/kg/d(2–4 divided doses)(2–4 divided doses)Diclofenac epolamineFlector®180 mg patch every 12 hrN/AEtodolac600–1000 mg daily20–30 kg: 400 mg daily(2–3 divided doses)31–45 kg: 600 mg daily46–60kg: 800 mg daily>60 kg: 1000 mg daily*Age 6–16 y**Based on ER product*Fenoprofen calciumNalfon®200–600 mg 3–4 x/dN/AMax 3200 mg/dFlurbiprofenAnsaid®200–300 mg dailyN/A(2–4 divided doses)IbuprofenMotrin®1200–3200 mg daily4–10 mg/kg/dose 3–4×/d(3–4 divided doses)Max 40 mg/kg/dIndomethacinIndocin®50–200 mg daily1–2 mg/kg/d(2–3 divided doses)(2–4 divided doses)Max 4 mg/kg/d, NTE: 150–200 mg/d*Age >2 y*KetoprofenIR: 150–300 mg dailyN/A(3–4 divided doses)ER: 100–200 mg dailyKetorolac tromethamineToradol®20 mg initially, 10 mg 4x/dN/AMax 5-d durationMeclofenamate sodium200–400 mg dailyN/A(3–4 divided doses)Mefenamic acidPonstel®500 mg initially, 250 mg every 6 h as needed (NTE: 1 wk)N/AMeloxicamMobic®7.5–15 mg daily0.125 mg/kg/dMax 7.5 mg daily*Age ≥2 y*Nabumetone500–2000 mg dailyN/A(1–2 divided doses)NaproxenNaproxen sodium: Anaprox®, Anaprox DS®, Aleve® (OTC)Naproxen: 250–500 mg 2×/d*Analgesia: 5–7 mg/kg/dose every 8–12 hNaproxen sodium: 200–500 mg 2×/d*Inflammatory disease: 10–15 mg/kg/d (2 divided doses)Naproxen DR: 375–500 mg 2×/dMax 1000 mg/dNaproxen: Naprosyn®*Age >2 y*OxaprozinDaypro®600–1200 mg daily Max 1800 mg daily (in divided doses)22–31 kg: 600 mg daily32–54 kg: 900 mg daily≥55 kg: 1200 mg daily*Age 6–16 y*PiroxicamFeldene®10–20 mg daily0.2–0.3 mg/kg/dMax 15 mg dailySulindacClinoril®150–200 mg 2×/d2–4 mg/kg/d(2 divided doses)Max 6 mg/kg/d, NTE: 400 mg/dTolmetin sodium600–1800 mg daily*Analagesia: 5–7 mg/kg/dose every 6–8 h(3 divided doses)Max 2000 mg daily*Inflammatory disease: 15–30 mg/kg/d (3–4 divided doses)NTE: 1800 mg/d*Age ≥2 y*CelecoxibCelebrex®100–400 mg daily10–25 kg: 50 mg 2×/d(1–2 divided doses)>25 kg: 100 mg 2×/d*Age ≥2 y*SalicylatesDiflunisal500–1000 mg dailyN/A(2–3 divided doses)Max 1500 mg dailyMagnesium salicylateNovosal®, Doan's Extra Strength®Novosal®: 600 mg 3–4× d, Max 4800 mg dailyN/ADoan's®: 934 mg every 6h as neededSalsalateAmigesic®, Salflex®3000 mg dailyN/A(2–4 divided doses)Choline magnesium trisalicylate500–1500 mg 2–3×/d30–60 mg/kg/d(3–4 divided doses)IR, immediate-release; ER, extended-release; DR, delayed-release; NTE, not to exceed.Search monographs [database on the Internet]. Indianapolis (IN); Facts & Comparisons 4.0; 2007 [cited 2007 Jul 23]. Nonsteroidal anti-inflammatory agents; [about 22 screens]. Available from: http://www.online.factsandcomparisons.com/search.aspx?book=DFC&Section=parentMono&search=nsaid.LexiComp Pediatric Database. http://www.lexi.com. 2007 Jul 23