RT Book, Section A1 Wood, Sarah M. A1 Rutstein, Richard M. A1 Steenhoff, Andrew P. A2 Shah, Samir S. SR Print(0) ID 6911114 T1 Chapter 52. HIV-Exposed Neonate and HIV At-Risk Child T2 Pediatric Practice: Infectious Disease YR 2009 FD 2009 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-148924-9 LK accesspediatrics.mhmedical.com/content.aspx?aid=6911114 RD 2024/04/18 AB Worldwide, more than 2 million children younger than 15 years are infected with HIV, with perinatal transmission the source of most of these infections.1,2 In the developed world, where prenatal testing and safe and effective antiretroviral prophylaxis are widely available, perinatally-acquired HIV has become almost entirely preventable. With early testing and treatment of HIV-infected mothers and their newborns the risk of perinatal HIV transmission can be reduced to less than 2%.3 The pediatric provider plays an essential role in disease reduction. By early identification of HIV-exposed infants, timely virologic testing and provision of postpartum HIV and opportunistic infection prophylaxis, pediatric care providers can intervene to dramatically reduce the risk of infection for the neonate.