RT Book, Section
A1 Sam-Agudu, Nadia A.
A1 John, Chandy C.
A2 Shah, Samir S.
SR Print(0)
ID 6926001
T1 Chapter 66. Malaria
T2 Pediatric Practice: Infectious Disease
YR 2009
FD 2009
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-148924-9
LK accesspediatrics.mhmedical.com/content.aspx?aid=6926001
RD 2024/04/18
AB Malaria  is  a  leading  cause  of  childhood  morbidity  and  mortality  worldwide.  The  burden  of  this  disease  is  largely  borne  by  children  in  sub-Saharan  Africa.  Approximately  60%  of  clinical  cases,  and  more  than  75%  of  the  greater  than  1  million  annual  deaths  from  malaria  occur  in  this  region,  mostly  in  children  younger  than  5  years.1,2  According  to  a  survey,  one  in  five  childhood  deaths  in  sub-Saharan  Africa  is  caused  by  malaria.3  In  the  United  States,  local  malaria  transmission,  which  was  once  endemic,  has  been  extremely  rare  since  the  1950s.4  However,  American  physicians  continue  to  encounter  patients  with  malaria,  mostly  immigrants,  refugees,  returned  travelers,  and  military  personnel,  who  acquired  their  infections  in  endemic  areas.  An  average  of  1200  malaria  cases  and  13  related  deaths  occur  in  the  United  States  every  year.4  Most  of  the  cases  are  imported,  most  are  caused  by  Plasmodium  falciparum,  and  most  are  acquired  in  Africa.4