RT Book, Section A1 Nigrovic, Peter A. A2 Rudolph, Colin D. A2 Rudolph, Abraham M. A2 Lister, George E. A2 First, Lewis R. A2 Gershon, Anne A. SR Print(0) ID 7019015 T1 Chapter 200. Diagnostic Testing in Rheumatology T2 Rudolph's Pediatrics, 22e YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-149723-7 LK accesspediatrics.mhmedical.com/content.aspx?aid=7019015 RD 2024/04/19 AB Laboratory and imaging studies rarely establish a definitive diagnosis of rheumatologic diseases in children. The prevalence of rheumatic diseases in childhood is low, and even very specific tests generate high false-positive rates unless there is a well-founded clinical suspicion for a particular illness, based upon an informed differential diagnosis guided by the history and physical exam. The utility of an assay will vary with the nature and stage of the illness. They can provide information that is useful for the evaluation and treatment.