RT Book, Section A1 Zulian, Francesco A2 Rudolph, Colin D. A2 Rudolph, Abraham M. A2 Lister, George E. A2 First, Lewis R. A2 Gershon, Anne A. SR Print(0) ID 7019700 T1 Chapter 206. Scleroderma T2 Rudolph's Pediatrics, 22e YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-149723-7 LK accesspediatrics.mhmedical.com/content.aspx?aid=7019700 RD 2024/04/18 AB Juvenile scleroderma syndromes are multisystem autoimmune rheumatic diseases whose unifying characteristic is the development of hard skin before age 16. They can be separated into two main categories: those with diffuse skin sclerosis involving many sites of the body together with internal organ involvement (juvenile systemic sclerosis [JSSc]) and those with circumscribed skin induration but no vascular or internal organ involvement (juvenile localized scleroderma [JLS]).