RT Book, Section A1 Moscona, Anne A1 Gershon, Anne A. A2 Rudolph, Colin D. A2 Rudolph, Abraham M. A2 Lister, George E. A2 First, Lewis R. A2 Gershon, Anne A. SR Print(0) ID 7021226 T1 Chapter 224. Viral Pathogenesis T2 Rudolph's Pediatrics, 22e YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-149723-7 LK accesspediatrics.mhmedical.com/content.aspx?aid=7021226 RD 2024/04/24 AB Viruses can only survive by entering and parasitizing the cells of a host. Because viruses cannot live independently of their interaction with the parasitized host cell, all viruses have evolved strategies for coexisting with cells, while these cells continue to carry out physiologic functions as part of specific tissues or organs. It is the complex interplay between viral and host properties that determines the relationship that the virus will experience with its host in vivo, whether resulting in disease or not. The interplay between viral and host features thus determines the pathogenesis of infection.