RT Book, Section
A1 Journeycake, Janna M.
A1 Chan, Anthony K. C.
A2 Rudolph, Colin D.
A2 Rudolph, Abraham M.
A2 Lister, George E.
A2 First, Lewis R.
A2 Gershon, Anne A.
SR Print(0)
ID 7040476
T1 Chapter 438. Diagnosis and Management of Thrombosis
T2 Rudolph's Pediatrics, 22e
YR 2011
FD 2011
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-149723-7
LK accesspediatrics.mhmedical.com/content.aspx?aid=7040476
RD 2024/04/19
AB Thrombosis,  defined  as  excessive  clotting,  has  three  main  causes:  reduced  blood  flow  (stasis),  increase  in  blood  coagulation  factors  (hypercoagulability),  and  abnormalities  in  the  vessel  wall.  Once  the  endothelium  is  injured,  platelet  adhesion  is  accompanied  by  platelet  aggregation  and  thrombin  formation.  This  process  is  usually  tightly  regulated  in  order  to  prevent  excessive  bleeding  or  clotting.  However,  at  times,  the  process  is  uncontrolled,  and  a  thrombus  can  form  in  excessive  amounts  or  in  an  unusual  place,  causing  harm.